Tadalafil 40 mg (Cialis): treating Erectile Dysfunction in men
tadalafil 40 mg is used primarily for the following purposes:
1. Treatment of erectile dysfunction (ED)
Mechanism for action:
-Tadalafil inhibits the enzyme phosphodiesterase-5 (PDE-5). This enzyme is responsible for the degradation of nitrogen monoxide (no)-dependent on cyclic guanosine monophosphate (cGMP) in the vascular smooth muscle of the penis. By inhibiting PDE-5, tadalafil increases cGMP levels, resulting in smooth muscle relaxation and increased blood flow to the penis, facilitating erection.
Effectiveness:
-help men with SD achieve and maintain sufficient erections for satisfactory sexual activity.
2. Treatment of pulmonary hypertension (HP)
Mechanism of action in HP:
-in pulmonary hypertension, tadalafil works by relaxing the muscles of the pulmonary arteries. This reduces pulmonary vascular resistance and relieves excessive pressure in the pulmonary circuit.
Benefits in HP:
-it can improve the exercise capacity, cardiac function and quality of life of patients with pulmonary hypertension.
It is important to note that tadalafil should be prescribed by a doctor and consideration should be given to possible side effects and contraindications. Some common side effects include headache, heartburn, nasal congestion, back pain, among others.